Contrast enhanced ultrasound in the assessment of focal liver lesions

Alina Popescu, Ioan Sporea, Roxana Sirli, Mirela Danilă, Alina Martie, Simona Bota, Adina Guta


The aim of this paper was to present our experience regarding an investigation into 100 focal liver lesions consecutively evaluated in the Department of Gastroenterology Timisoara.

Patients and methods: we included 100 consecutive contrast enhanced ultrasonographies (CEUS) performed in patients with focal liver lesions. The arterial phase was considered to be between 10-35 seconds from the IV administration, the venous phase between 35-120 seconds, while the late phase was considered over 120 seconds.

Results: We analyzed 100 lesions from 82 patients. In 64 cases the patients were known to have liver cirrhosis.

According to the CEUS description the lesions were classified as follows: 17 hemangiomas, 3 focal nodular hyperplasia, 2 adenomas, 3 fluid collections, 1 case of normal liver, 6 cases of regenerative nodules, 24 hepatocellular carcinomas (HCC), 7 HCCs incompletely treated percutaneously, 16 completely treated HCCs, 10 cases of liver metastases; in 11 cases the lesions could not be classified according to CEUS criteria.

In conclusion: CEUS is a promising method for the evaluation of liver focal lesions, which can replace CT or RMI in many cases. In 11%of the evaluated cases the CEUS pattern was not typical for any specific liver lesion.


contrast enhanced ultrasound; liver lesions; hepatocellular carcinoma

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